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Proses infiltrasi ini melibatkan beberapa mekanisme. Sel kanker melepaskan enzim yang dapat memecah matriks ekstraseluler (ECM), yaitu 'lem' yang menyatukan sel-sel dalam jaringan. Dengan merusak ECM, sel kanker dapat membuka jalan untuk merangsek ke jaringan lain. Selain itu, sel kanker juga dapat bergerak secara aktif, memanfaatkan berbagai mekanisme molekuler untuk berpindah tempat. Kemampuan ini adalah kunci bagi penyebaran kanker atau metastasis, yang merupakan salah satu tahap paling berbahaya dari penyakit ini.
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